Antiprotozoal Drugs
نویسنده
چکیده
GENERIC NAME PAGE Amodiaquine 614 Atovaquone 616 Chloroguanide 615 Chloroquine 613 Dapsone 615 Diloxanide 609 Eflornithine 610 Hydroxychloroquine 614 Iodoquinol 608 Mefloquine 616 Meglumine antimonate 611 Melarsoprol 610 GENERIC NAME PAGE Metronidazole 608 Nifurtimox 610 Paromomycin 609 Pentamidine 609 Primaquine 614 Pyrimethamine 614 Quinine 615 Sodium stibogluconate 611 Suramin 609 Trimethoprim 614 Tryparsamide 610
منابع مشابه
Determination of antiprotozoal drug mechanisms by metabolomics approaches
The discovery, development and optimal utilization of pharmaceuticals can be greatly enhanced by knowledge of their modes of action. However, many drugs currently on the market act by unknown mechanisms. Untargeted metabolomics offers the potential to discover modes of action for drugs that perturb cellular metabolism. Development of high resolution LC-MS methods and improved data analysis soft...
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In the present scenario of protozoal infections, new drugs are urgently needed to treat and control infections such as malaria, sleeping sickness, Chagas disease, leishmaniasis and intestinal infections, which aff ect millions of people each year. In this review, we are focusing on articles related to antiprotozoal essential oils extracted from plants that have been published during the last 20...
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The Leguminosae (Fabaceae) is the second-largest family of flowering plants and contains 657 genera and about 16400 species. It includes more important drugs than any other family. Apart from a report on description of the species in Iran, the literature lists only reports of photosynthesis and carbon dioxide exchange in the plant, and also three reports on isolation of alkaloids named smirnovi...
متن کاملπ-Delocalized Lipophilic Cations as New Candidates for Antimalarial, Antitrypanosomal and Antileishmanial Agents: Synthesis, Evaluation of Antiprotozoal Potency, and Insight into Their Action Mechanisms.
The search for new drugs that could treat tropical protozoan diseases, such as malaria or neglected tropical diseases (NTDs), motivates many medicinal chemists. New classes of antiprotozoal drugs that act through a novel mechanism of action must be developed. This review presents our efforts toward finding new candidate treatments for malaria, American trypanosomiasis, human African trypanosomi...
متن کاملSynthetic Nitroimidazoles: Biological Activities and Mutagenicity Relationships
Parasitic and bacterial infections affecting the gastrointestinal tract represent a significant cause of morbidity and mortality worldwide. Nitroheterocyclic drugs have been available since the early 1960s for the treatment of anaerobic protozoa. The application of these drugs has widened and they are presently used to treat anaerobic pathogenic bacteria and protozoa. 5-nitroimidazoles are a we...
متن کاملThe skin secretion of the amphibian Phyllomedusa nordestina: a source of antimicrobial and antiprotozoal peptides.
Antimicrobial peptides (AMPs) from the dermaseptin and phylloseptin families were isolated from the skin secretion of Phyllomedusa nordestina, a recently described amphibian species from Northeastern Brazil. One dermaseptin and three phylloseptins were chosen for solid phase peptide synthesis. The antiprotozoal and antimicrobial activities of the synthetic peptides were determined, as well as t...
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